Your Polynucleotides Questions Answered
Polynucleotides continue to attract interest from both practitioners and patients as a regenerative addition to aesthetic treatment plans. Given the range of questions that come up around this treatment category, we’ve put together this FAQ-style guide to address some of the most common queries. As always, this content is intended for qualified aesthetic professionals and general educational purposes, and specific clinical decisions should always be guided by manufacturer training, product IFUs and individual patient assessment.
What are polynucleotides?
Polynucleotides are naturally derived fragments of DNA, typically sourced from purified salmon or trout sperm, that are formulated into injectable products for aesthetic use. They are designed to support the skin’s own repair and regeneration processes, and are often positioned within the biostimulator and skin-conditioning category of treatments rather than as volumising fillers.
How do polynucleotides differ from dermal fillers?
While dermal fillers are generally designed to add volume or contour to specific areas, polynucleotides work differently, aiming to support skin quality, hydration and the tissue’s regenerative capacity. Some practitioners describe polynucleotides as working on the underlying skin environment rather than providing structural volume, which is why they are sometimes used alongside filler treatments as part of a broader plan, subject to individual assessment.
What areas can be treated?
Polynucleotides are commonly discussed in relation to the under-eye area, the face more broadly, the neck, and the scalp, though specific indications depend on the individual product and its regulatory approval. Practitioners should always refer to the manufacturer’s guidance for the specific product they are using to confirm approved treatment areas.
How many sessions are typically needed?
Treatment plans vary depending on the product used, the area treated and the individual patient’s skin condition and goals. Many practitioners discuss a course of sessions spaced several weeks apart, sometimes followed by periodic maintenance treatments. Because results depend on individual biological response, it is important that patients understand that outcomes and timelines can vary and are not guaranteed.
What side effects might patients experience?
As with any injectable treatment, temporary reactions such as redness, swelling, tenderness, or small bumps at the injection site are commonly reported and generally resolve within a short period. Practitioners should provide clear aftercare advice and ensure patients understand how to contact the clinic if they have any concerns following treatment.
Who might not be suitable for polynucleotide treatment?
Suitability should always be assessed on an individual basis through a thorough consultation and medical history review. Certain allergies, sensitivities, medical conditions or medications may mean a patient is not a suitable candidate, and practitioners should follow the contraindications listed in the specific product’s Instructions for Use.
Where can practitioners access training and products?
Because technique, injection approach and patient selection differ between polynucleotide products, formal manufacturer or accredited third-party training is strongly recommended before offering these treatments. Fox Pharmacy supplies a range of polynucleotide products to qualified aesthetic professionals and can help point practitioners towards suitable training routes.
If you have further questions about polynucleotide products or would like to explore our range, get in touch with the Fox Pharmacy team today.