Sunekos Perfoma vs Profhilo

Sunekos Performa and Profhilo are both widely recognised names within the bio-remodelling and skin booster space, and practitioners are often asked by patients, or ask themselves, how the two compare. Rather than favouring one over the other, this article aims to set out the general compositional approach, typical use cases, and practical considerations associated with each product type, to support informed decision-making.

Compositional Approach

Profhilo is a hybrid hyaluronic acid product, combining high and low molecular weight hyaluronic acid in a stabilised formulation without chemical cross-linking agents. This composition is designed to disperse through the tissue from a small number of injection points, with the intention of stimulating the skin’s own production of collagen and elastin, a mechanism often referred to as bio-remodelling.

Sunekos Performa, by contrast, is typically formulated with a blend of hyaluronic acid and amino acids, positioned by its manufacturer as supporting the skin’s natural synthesis of both collagen and elastin through a different biochemical pathway. It is generally administered via a series of multiple small injections across the treatment area, similar in technique to a traditional skin booster.

Typical Use Cases

Both products are generally marketed toward patients seeking improvements in skin quality, laxity, and hydration, rather than volumisation. In practice, practitioners may consider factors such as:

• Treatment area – both are commonly used on the face, neck, décolletage, and hands, with product-specific guidance on injection points and depth.
• Patient presentation – practitioners often assess the degree of skin laxity, fine lines, and overall skin quality when considering which approach may be more suitable for a given patient.
• Treatment course – both product types are typically administered as part of a course of sessions, with maintenance treatments often suggested to help sustain results, which vary between individuals.

Practical Considerations for Practitioners

When evaluating either product for inclusion in a treatment menu, practitioners may wish to consider the following:

• Manufacturer training and protocols: each product has its own recommended injection technique, and practitioners should complete relevant training before use.
• Patient consultation: setting realistic expectations is important, as outcomes are not guaranteed and depend on individual factors including skin condition, age, and lifestyle.
• Clinical evidence base: practitioners should review the published literature and manufacturer data available for each product to inform their own clinical judgement.
• Patient budget and treatment planning: as both typically involve a course of treatments, cost and scheduling are practical factors worth discussing upfront.

Two Established Options, Not a Straightforward Winner

Ultimately, Sunekos Performa and Profhilo represent two different formulation approaches within the broader bio-remodelling and skin booster category, and neither should be considered universally superior. The right choice for a given patient often depends on individual clinical assessment, practitioner experience, and the specific outcomes being targeted, and many practitioners find value in understanding both approaches to broaden their treatment options.

To discuss the skin booster and bio-remodelling products available through Fox Pharmacy, or to browse our current range, feel free to get in touch with our team – we are happy to help you find the right products for your practice.